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Table 1 The biochemical parameters of CON, STZ-DM, DM-R0.1 and DM-R1 rats

From: Resveratrol retards progression of diabetic nephropathy through modulations of oxidative stress, proinflammatory cytokines, and AMP-activated protein kinase

  CON (n = 11) STZ-DM (n = 7) DM-R0.1 (n = 11) DM-R1 (n = 15)
Body weight (g) 420.77 ± 8.88 280.29 ± 9.41* 330.77 ± 9.45* 312.81 ± 10.55*
Plasma glucose (mg/dl) 137.15 ± 10.86 566.33 ± 45.24* 444.17 ± 22.90* 376.48 ± 35.56*
Plasma insulin (μg/l) 2.00 ± 0.28 0.11 ± 0.06* 0.78 ± 0.25* 0.86 ± 0.12*
Plasma cholesterol (mg/dl) 67.30 ± 9.63 111.13 ± 16.98* 59.51 ± 7.16 48.05 ± 5.64
Plasma triglycerides (mg/dl) 88.27 ± 11.41 166.41 ± 35.43* 55.84 ± 7.47* 63.52 ± 9.20
Blood urea nitrogen (mg/dl) 16.27 ± 0.94 25.01 ± 3.90* 19.97 ± 1.52* 21.73 ± 1.72*
Plasma creatinine (mg/dl) 0.37 ± 0.04 0.59 ± 0.10* 0.41 ± 0.04 0.48 ± 0.04
  1. Values were expressed as means ± standard error (n = 7~15 per group). CON: non-diabetic control, STZ-DM: streptozotocin-induced diabetes, DM-R0.1: DM treated with RSV (0.1 mg/kg/day) for 7 days, DM-R1: DM treated with RSV (1 mg/kg/day) for 7 days.
  2. *: P < 0.05 vs. control, †: P < 0.05 vs. STZ-DM, ‡: P < 0.05 vs. DM-R0.1.