Table 2 Statistical evaluation of nucleosomes compared to CEA and CA 19-9 for colorectal carcinoma
Parameter | Cutoff value | Sensitivity % | Specificity % | J index | Accuracy % | Kappa | PPV % | NPV % | ROC curve area | |
|---|---|---|---|---|---|---|---|---|---|---|
Value | P | |||||||||
CA 19-9 | 28 u/ml | 36.4 | 88.9 | 26 | 41 | 0.121 | 0.088 | 91.56 | 21.62 | 0.524 |
CEA | 3.56 ng/ml | 56.2 | 100 | 55.8 | 62.2 | 0.290 | <0.001 | 100 | 30.40 | 0.808 |
Nucleosomes | 421 | 100 | 100 | 100 | 100 | 1.00 | <0.001 | 100 | 100 | 1.0 |