Figure 2
Interaction analysis between arsenic exposure level and GSTO A140D-O2 5'UTR(-183)A/G-O2 N142D diplotype on UC risk. ** The case number of subgroup with GSTO w/v or GSTO v/v and low level exposure was assumed as 0.1 to calculate 95% CI of EFw/v and EFv/v, respectively. HR: adjusted for age/gender/cigarette smoking/education level. Abbreviations HR: hazard ratio; CAE: cumulative arsenic exposure; EF: etiologic fraction; UC: urothelial carcinoma; w/w: wild type homozygous; w/v: heterozygous; v/v: variant homozygous.