Table 3 Univariate analysis of urothelial carcinoma risk by genotypes of GST superfamily
| Â | Â | Urothelial carcinoma | ||
|---|---|---|---|---|
| Â | No (%) | Case no. | HR (95% CI) | P value |
GSTM1 | Â | Â | Â | Â |
   Non-null | 312 (42.5) | 18 | ref |  |
   Null | 422 (57.5) | 23 | 0.94(0.51-1.74) | 0.84 |
GSTT1 | Â | Â | Â | Â |
   Non-null | 368 (50.3) | 14 | ref |  |
   Null | 363 (49.7) | 27 | 1.91(1.00-3.65)* | 0.05 |
GSTP1-105 | Â | Â | Â | Â |
   AA | 491 (64.8) | 25 | ref |  |
   AG | 192 (25.3) | 10 | 1.07(0.51-2.23) | 0.86 |
   GG | 75 (9.9) | 5 | 1.71(0.64-4.56) | 0.29 |
   AG+GG | 267 (35.2) | 15 | 1.21(0.64-2.31) | 0.56 |
GSTO1-140 | Â | Â | Â | Â |
   CC | 521 (70.0) | 27 | ref |  |
   CA | 199 (26.7) | 9 | 0.81(0.38-1.73) | 0.59 |
   AA | 24 (3.3) | 2 | 2.11(0.50-8.99) | 0.31 |
   CA+AA | 223 (30.0) | 11 | 0.92(0.45-1.85) | 0.80 |
GSTO2-(-183) | Â | Â | Â | Â |
   AA | 487 (64.2) | 26 | ref |  |
   AG | 234 (30.9) | 11 | 0.73(0.36-1.48) | 0.38 |
   GG | 37 (4.9) | 4 | 2.58(0.88-7.52) | 0.08 |
   AG+GG | 271 (35.8) | 15 | 0.90(0.48-1.71) | 0.75 |
GSTO2-142 | Â | Â | Â | Â |
   AA | 428 (56.6) | 20 | ref |  |
   AG | 283 (37.4) | 17 | 1.14(0.60-2.19) | 0.69 |
   GG | 45 (6.0) | 4 | 2.62(0.88-7.83) | 0.08 |
   AG+GG | 328 (43.4) | 21 | 1.28(0.69-2.37) | 0.43 |
GSTO1(140)/O2(-183)/O2(142) | Â | Â | ||
   CAA/CAA | 397 (53.8) | 18 | ref |  |
   CAA/AGG | 163 (22.1) | 7 | 0.83(0.34-1.98) | 0.66 |
   AGG/AGG | 20 (2.7) | 2 | 3.08(0.70-13.54) | 0.13 |
   Others | 158 (21.4) | 11 | 1.55(0.73-3.28) | 0.25 |