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Table 1 Levels of some clinical serum indicators in the animals

From: Discovery of serum biomarkers of alcoholic fatty liver in a rodent model: C-reactive protein

Indicators Normal
(n= 7)
AFL
(n= 6)
HF-NAFL (n= 4) HL-NAFL (n= 6) LF§
(n= 5)
BW (g) 270 ± 5/457 ± 14§ 275 ± 3 418 ± 28§ 565 ± 29§,* ND
AST (U/L) 154 ± 25 148 ± 34c 164 ± 31 181 ± 63 199 ± 37*
ALT (U/L) 56 ± 15 41 ± 13c 48 ± 17 57 ± 22 74 ± 19*
TBIL
(mg/dl)
0.70 ± 0.06 0.62 ± 0.09a, b, c 0.78 ± 0.04 0.75 ± 0.05 0.84 ± 0.10*
TG
(mg/dl)
51 ± 16 58 ± 10a 91 ± 14** 56 ± 11 48 ± 14
TCHO
(mg/dl)
61 ± 10 68 ± 8 72 ± 10 71 ± 12 61 ± 17
  1. BW, body weight; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TBIL, total bilirulin; TG, triglyceride; TCHO, total cholesterol; AFL, alcoholic fatty liver; HF-NAFL, high fructose-induced non-alcoholic fatty liver; HL-NAFL, high lipid-induced non-alcoholic fatty liver; LF, liver fibrosis. Indicators for predicting liver function include GOT, GPT, and bilirubin and for predicting fat cells include triglyceride and cholesterol. Rats were treated before the age of 6 weeks and sacrificed by the ages of 10 and §18 weeks. ND, Non-detection. The p value was calculated according to Student's t-test. * p < 0.05 and **p < 0.01 as compared to normal controls. A significant change (p < 0.05) was also determined for AFL rats compared to aHF-NAFL, bHL-NAFL, and cLF rats.