Skip to main content

Table 3 Serum concentration of C reactive protein (CRP) and haptoglobin (Hp) in clinical patients

From: Discovery of serum biomarkers of alcoholic fatty liver in a rodent model: C-reactive protein

Patients (n) Fibrosis
(n, %)
P-steatosis
(n, %)
HAI
(n, %)
CRP
(mg/L)
Hp
(g/L)
Healthy (16) ND ND ND 1.58 ± 0.48 1.13 ± 0.63
NASH (19) F1~F2
(19, 100%)
Stage 0~1
(7, 37%)
Stage 0~4
(18, 95%)
ND 0.74 ± 0.39*
   Stage 2~3
(12, 63%)
Stage 5~13
(1, 5%)
  
HCV-
liver fibrosis (17)
F1~F2
(7, 41%)
Stage 0~1
(15, 88%)
Stage 0~4
(2, 12%)
1.31 ± 0.44* 0.45 ± 0.58*,#
  F3~F4
(10, 59%)
Stage 2~3
(2, 12%)
Stage 5~13
(15, 88%)
  
  1. The fibrotic stage was determined according to the Metavir classification. The stage of p-steatosis was determined according to the fatty change. HAI, necroinflammatory scores. NASH, non-alcoholic steatohepatitis; ND, not determined.* p < 0.05, compared to healthy controls. # p < 0.05, compared to NASH. The significance was calculated according to Student's t-test. The data are presented as the mean ± SEM.