Figure 3

Average of rotarod performance of mouse which received intracranial human mesenchymal stem cells transplantation at sequential periods. Average of latency to fall from rotarod (in seconds) of mice after serial hMSCs implantation through intracranial injection was compared every 8 weeks. Rotarod performance of SCA2 transgenic mice (n = 5) was not significantly improved by serial intracranial hMSCs transplantation at 33-40 weeks of age (p = 0.055). hMSCs, Statistical analysis between each group was performed by one-way ANOVA (p = 0.055), and between Control-Wt (n = 16) and Control-Tg group (n = 10) was performed by t test (p < 0.05).