Blood phosphorus levels in 8-week-old KYF and Kbus mice, showing Kbus mice to be hypophosphatemic (right panel). No significant variation was observed between homozygous and heterozygous Kbus females, indicating the hypophosphatemic character to be fully dominant. n = 3. Also refer to Additional file 3, Table S2. Serum ALP levels in 14-week-old KYF and Kbus mice, showing extremely high activities in Kbus (left panel). n = 5. Asterisks indicate the statistical significant difference for the values of age-matched KYF samples (p < 0.01).