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Figure 4 | Journal of Biomedical Science

Figure 4

From: System in biology leading to cell pathology: stable protein-protein interactions after covalent modifications by small molecules or in transgenic cells

Figure 4

Interaction of calmodulin-binding site of MARCKS with calmodulin (CAM) in the presence of xanthurenic acid in MEF cells WT, Bid -/- and DKO. Western blot analysis with antibody against ED sequence of MARCKS of proteins immunoprecipitated with CAM: WT lanes1-3, lane 1-control, lanes (2-3) in the presence of xanthurenic acid: lane 2-10 μM, lane 3- 20 μM; Bid -/- lanes 4-6: lane 4-control, lanes (5-6) in the presence of xanthurenic acid: lane 5-10 μM, lane 6- 20 μM; DKO lanes 7-9; lane 7-control, lanes (8-9) in the presence of xanthurenic acid: lane 8-10 μM, lane 9- 20 μM.

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