Figure 1From: BACE-1 inhibition prevents the γ-secretase inhibitor evoked Aβ rise in human neuroblastoma SH-SY5Y cellsMolecular structures of the inhibitors. A. Molecular structure of the BACE inhibitor as described in Charrier et al., 2008 [22]. B. Structure of the γ-secretase inhibitor LY450139 (semagacestat, Audia et al., 2007 [21]).Back to article page