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Figure 1 | Journal of Biomedical Science

Figure 1

From: The discovery of potential acetylcholinesterase inhibitors: A combination of pharmacophore modeling, virtual screening, and molecular docking studies

Figure 1

The best Pharmacophore model (Hypo1) of AChE inhibitors generated by the HypoGen module. (A) Three dimensional (3D) spatial arrangement and geometric parameters of Hypo1 and distance between pharmacophore features (Ã…). (B) Best Pharmacophore features model. (C) Hypo1 mapping with one of the most active compound 7. (D) Hypo1 mapping with one of the least active compound 44. Pharmacophore features are color-coded with light-blue for hydrophobic feature and magenta for hydrogen-bond donor.

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