Figure 5

The binding structures of compounds (A) NSC659829 and (B) NSC35839 after docking into the catalytic gorge of huAChE. Residues at a distance of less than 4 Å from the compounds are represented as 0.1Å atom-colored sticks. W86 and W286 are displayed as 0.2Å atom-colored sticks. The compounds are shown as 0.3Å stick models (carbon atom in green for (A) and maroon for (B), oxygen atom in red, nitrogen atom in blue, and sulfur atom in yellow).