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Figure 3 | Journal of Biomedical Science

Figure 3

From: Acid-sensing ion channel 3 mediates peripheral anti-hyperalgesia effects of acupuncture in mice inflammatory pain

Figure 3

ASIC3 was increased in lumbar DRGs in intraplantar CFA-induced hyperalgesia. ASIC3 was increased in lumbar DRGs in intraplantar CFA-induced hyperalgesia and decreased by EA at ST36 acupoint in mice. (a), (b) ASIC3 immunoreactive neurons were found in lumbar DRGs in both ipsilateral and contralateral site of saline-injected group. (c) ASIC3 immunoreactive neurons were increased in ipsilateral site of CFA-induced inflammation. (d) ASIC3 immunoreactive neurons were not increased in contralateral site of CFA-induced inflammation. (e) CFA-induced increase of ASIC3 was attenuated by EA in ipsilateral site of inflammation. (f) ASIC3 immunoreactive neurons were not altered by EA in contralateral site of inflammation. Arrows indicated immunoreactive neurons of ASIC3.

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Journal of Biomedical Science

ISSN: 1423-0127