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Figure 4 | Journal of Biomedical Science

Figure 4

From: Acid-sensing ion channel 3 mediates peripheral anti-hyperalgesia effects of acupuncture in mice inflammatory pain

Figure 4

ASIC3 was increased in lumbar DRGs in both intraplantar carrageenan- and CFA-induced hyperalgesia. ASIC3 was increased in lumbar DRGs in both intraplantar carrageenan- and CFA-induced hyperalgesia and further attenuated by EA at ST36 acupoint in mice. (a) ASIC3 proteins were increased in ipsilateral site of carrageenan-mediated inflammation and ameliorated by EA at ST36 acupoint (b) ASIC3 proteins were not changed in contralateral site of carrageenan-mediated inflammation and EA stimulation. (c) ASIC3 proteins were increased in ipsilateral site of CFA-induced inflammation and attenuated by EA at ST36 acupoint (d) ASIC3 proteins were not altered in contralateral site of CFA-mediated inflammation and EA stimulation.

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