Effects of HDME (3~30 μmol/kg, p.o.) on the enhanced pause (P
). Effects of HDME (3~30 μmol/kg, p.o.) on the enhanced pause (Penh) (A), inflammatory cells (B), and cytokines (C) in sensitized mice which received aerosolized methacholine (6.25~50 mg/ml) 2 days after primary allergen challenge. # p < 0.05, ## p < 0.01, and ### p < 0.001, compared to the non-challenged group. * p < 0.05, ** p < 0.01, and *** p < 0.001, compared to the control (vehicle) group. The number of mice in each group was 10. Total, total cells; Mac, macrophages; Lym, lymphocytes; Neu, neutrophils; Eos, eosinophils; IL, interleukin; IFN, interferon; TNF, tumor necrosis factor.