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Figure 8 | Journal of Biomedical Science

Figure 8

From: Hesperetin-7,3'-O-dimethylether selectively inhibits phosphodiesterase 4 and effectively suppresses ovalbumin-induced airway hyperresponsiveness with a high therapeutic ratio

Figure 8

Effects of subcutaneously administered rolipram (A) and HDME (B). Effects of subcutaneously administered rolipram (A) and HDME (B) on the duration of xylazine (10 mg/kg, i.p.)/ketamine (70 mg/kg, i.p.)-induced anesthesia in mice. Rolipram was administered 0.25 h and HDME 1 h before anesthesia. ** p < 0.01, *** p < 0.001, compared to the vehicle (control). Each value represents the mean ± SEM. The number of mice in each group was 10.

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