Figure 6
Ectopic Dpp-induced apoptosis is mediated through DTAK1. (A) Ectopic expression of brk using 24B-gal4 induced cell death. (B) Mesodermal overexpression of brk did not suppress cardial apoptosis in raw mutants (brackets). (C, D) Excessive cell death was induced by overexpression of dTAK1 using Act5C- or 24B-gal4 drivers. (E, F) Overexpression of dominant negative dTAK1DN using Act5C- or 24B-gal4 drivers inhibited apoptosis. (G) Constitutively-expressed dTAK1DN suppressed ectopic dpp-induced apoptosis. (H) Mesodermal expression of dTAK1DN inhibited cardial apoptosis in raw mutants.