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Figure 4 | Journal of Biomedical Science

Figure 4

From: Immortalized mesenchymal stem cells: an alternative to primary mesenchymal stem cells in neuronal differentiation and neuroregeneration associated studies

Figure 4

Proliferation capacity of three different kinds of MSCs and trilineage potential of IMSCs. A: Growth curve of three different kinds of MSCs (primary MSCs, IMSCs, and IMSCs Cre T antigen). The number of viable cells gradually increased from D0 and attained peak at D3 in all three kinds of MSCs. And then, viable cells number decreased sharply from D3 to D5. The viable cells number of IMSCs was significantly more than another two kinds of MSCs from D2 to D5 (*, p < 0.01 by one-way ANOVA). The tendence of cell growth of IMSCs was reversible with cre recombination. B: Osteocytes, chondrocytes and adipocytes were induced from primary MSCs and IMSCs. IMSCs displayed the same mesodermal trilineage differentiation potential as MSCs (Scale Bar = 20 μm).

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