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Figure 3 | Journal of Biomedical Science

Figure 3

From: Inhibition of BMP signaling in P-Cadherin positive hair progenitor cells leads to trichofolliculoma-like hair follicle neoplasias

Figure 3

Blocking BMP signaling in hair progenitor cells induces ordered tumorigenesis. (A1-A3) H&E images from different time points of Nse-Noggin animals show morphological features of neoplasias at different stages of tumorigenesis. Note the progressive development of abnormal secondary hair follicles. (B1-B3) show the typical transgene expression pattern at different stages of tumorigenesis. Note that transgene expression is restricted to hair follicle cells and not other cells. Bar = 40 μm.

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Journal of Biomedical Science

ISSN: 1423-0127