Figure 4
From: A novel role of sesamol in inhibiting NF-κB-mediated signaling in platelet activation
Effects of sesamol on the inhibition of [Ca2+]i mobilization and platelet aggregation in the presence of various inhibitors in collagen-activated platelets. Washed platelets were preincubated with sesamol (25 μM) or 0.5% DMSO in the presence of BAY11-7082 (10 μM), SQ22536 (100 μM), or H89 (5 μM), followed by the addition of collagen (1 μg/ml) to trigger (A) [Ca2+]i mobilization and (B) platelet aggregation for 6 min as described in "Methods". The profiles (A and B) are representative examples of four similar experiments.