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Table 4 Summary of MSI analysis for DMBA-induced mammary carcinoma and liver of rats fed the diet supplemented with copper 1.3 mg/ml (42.6 mg Cu/kg diet) and resveratrol 0.1 mg/ml (0.2 mg/kg bw)

From: Effect of Cu supplementation on genomic instability in chemically-induced mammary carcinogenesis in the rat

Marker

Tumor (n = 10)

Number of rat/Tumor determination

Liver (n = 8)

Number of rat

 

2/2

11/1

4/2

5/5

7/3

8/1

8/4

9/1

9/2

10/2

1

2

3

4

5

6

7

8

D1Mgh6 127 bp

+

+

+

+

+

+

+

+

+

+

+

+

L

+

+

L

+

+

D3Mgh7 128 bp

+

+

+

+

+

+

+

+

+

+

+

+

+

+

+

+

+

+

D3Mgh9 128 bp

L

L

+

L

L

+

+

+

+

+

+

+

L

+

+

+

+

L

D8Mgh11 146 bp

+

+

+

+

+

+

+

+

+

+

+

+

+

+

+

+

+

+

  1. L - loss of heterozygosity
  2. + - genomic stability