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Table 3 Survival analysis for rs12425791 and rs11833579 and risk of death or stroke recurrence among first-ever ischemic stroke patients

From: Association between genetic variant on chromosome 12p13 and stroke survival and recurrence: a one year prospective study in Taiwan

SNP

Neither death nor

stroke recurrence

observed (n = 706)

Either Death

or stroke

recurrence

(n = 59)

   
 

No.

(%)

No.

(%)

HR* (95% CI)

P-value

q-value‡

rs12425791

       

   GG

421

(93.1)

26

(5.8)

1.0†

  

   GA

244

(90.7)

24

(9.0)

1.55(0.88-2.74)

0.131

0.149

   AA

41

(82.0)

9

(18.0)

3.30(1.53-7.12)

0.002

0.018

   GG

421

(94.2)

26

(5.8)

1.0

  

   GA+AA

285

(89.6)

33

(10.4)

1.83(1.08-3.08)

0.024

0.038

   GG+GA

665

(93.0)

50

(7.0)

1.0

  

   AA

41

(82.0)

9

(18.0)

2.76(1.34-5.68)

0.006

0.018

rs11833579

       

   GG

319

(94.4)

19

(5.6)

1.0†

  

   GA

299

(92.0)

26

(8.0)

1.53(0.84-2.80)

0.164

0.164

   AA

86

(86.0)

14

(14.0)

2.68(1.31-5.48)

0.007

0.018

   GG

319

(94.4)

19

(5.6)

1.0

  

   GA+AA

385

(90.6)

40

(9.4)

1.80(1.03-3.13)

0.039

0.052

   GG+GA

618

(93.2)

45

(6.8)

1.0

  

   AA

86

(86.0)

14

(14.0)

2.15(1.15-4.02)

0.017

0.034

  1. *: Adjusted for age, gender, hypertension, diabetes mellitus, cigarette smoking and alcohol drinking, obesity, and NIHSS at the beginning
  2. †: p for trend < 0.05
  3. ‡: False discovery rate (FDR) was controlled using the Benjamini-Hochberg procedure
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Journal of Biomedical Science

ISSN: 1423-0127