| |
Odds ratio (95% CI) (Univariate analysis)
|
P value
|
Odds ratio (95% CI) (Multivariate analysis)
|
P value
|
|---|
|
Genotype
| | | | |
|
Asp/Asp(n = 87)
|
reference
| |
reference
| |
|
Gly/Gly + Gly/Asp(n = 367)
|
1.957 (1.220-3.139)
|
0.005
|
2.008 (1.210-3.332)
|
0.007
|
|
Male
|
2.240 (1.516-3.309)
|
<0.001
|
1.969 (1.154-3.358)
|
0.013
|
|
Age, year
|
1.033 (1.016-1.050)
|
<0.001
|
1.037 (1.017-1.057)
|
<0.001
|
|
Hypertension
|
1.609 (1.089-2.376)
|
0.017
|
1.153 (0.738-1.803)
|
0.531
|
|
Diabetes mellitus
|
2.054 (1.305-3.232)
|
0.002
|
1.847 (1.133-3.009)
|
0.014
|
|
Smoking history
|
1.981 (1.302-3.012)
|
0.001
|
1.521 (0.912-2.536)
|
0.108
|
|
Hypercholesterolemia history
|
1.559 (1.063-2.286)
|
0.023
|
1.308 (0.841-2.032)
|
0.233
|
|
Body mass index(kg/m2)
|
1.012 (0.960-1.066)
|
0.667
|
1.992 (0.936-1.052)
|
0.796
|
|
Total cholesterol(mmol/L)
|
1.263 (1.037-1.538)
|
0.020
|
1.295 (1.028-1.631)
|
0.028
|
|
Serum creatitnine(μmol/L)
|
1.016 (1.007-1.024)
|
<0.001
|
1.004 (0.995-1.014)
|
0.392
|
- IRS: insulin receptor substrate; CAD: coronary artery disease; CI: confidence interval.
- * Totally, 284 CAD patients and 170 control subjects were included in analysis.
