Gly1057Asp polymorphism of insulin receptor substrate-2 is associated with coronary artery disease in the Taiwanese population

Table 5 Linear regression analysis for prediction of HOMA-IR index

Factors	Simple regression		Multiple regression
	Unstandardized coefficient (B)	P value	Unstandardized coefficient (B)	Standardized coefficient (beta)	P value
Gly1057Asp polymorphism in IRS-2
Asp/Asp(n = 41)	reference		reference	reference
Gly/Gly(n = 69) + Gly/Asp(n = 80)	0.007	0.902	−0.023	−0.029	0.678
Age(year)	−0.002	0.245	−0.003	−0.107	0.147
Diabetes mellitus	0.194	<0.001	0.151	0.213	0.003
Hypertension	0.103	0.037	0.078	0.115	0.121
Male	0.019	0.697	−0.032	−0.048	0.574
Smoking	0.013	0.800	−0.012	−0.017	0.830
Total cholesterol(mmol/L)	0.033	0.197	0.040	0.114	0.103
Serum creatinine(μmol/L)	0.002	0.019	0.003	0.206	0.007
Body mass index(kg/m²)	0.023	<0.001	0.017	0.189	0.008

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