Figure 4

Bar graphs show percentage changes in NMDA-induced increases in MAP 10 min and 40 min after intravenous injection of ketamine (2 mg/kg, left part; 4 mg/kg, right part) applied immediately (0 min) or at 10 min and 30 min after intravenous injection of ethanol (0.16 g). The peak magnitude of NMDA-induced increase in MAP immediately prior to application of ethanol and/or ketamine is taken as control (100%). *Statistically significant difference between groups analyzed using two-way ANOVA followed by Bonferroni post-test.