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Figure 5 | Journal of Biomedical Science

Figure 5

From: Dual regulation by ethanol of the inhibitory effects of ketamine on spinal NMDA-induced pressor responses in rats

Figure 5

(a) Left panel: western blot analysis of the levels of phosphoserine 896 on GluN1 subunit (pGluN1-serine 896), phosphoserine 897 on GluN1 subunit (pGluN1-serine 897), and GluN1 subunit (GluN1) in lateral horn regions of T7-T9 segments of rat spinal cord without (control) and at 10 min and 30 min after intravenous injection of ethanol (EtOH, 0.025 g). The percentage changes in the ratio of pGluN1 (serine 896 and serine 897) to GluN1 are shown in the right panel. The ratio of pGluN1 to GluN1 in rats without administration of ethanol is taken as control (100%). Panels (b) and (c) are similar to panel (a) except that 0.16 g and 0.32 g ethanol were injected, respectively. Values denote mean + SEM from 4-5 separate experiments. *Statistically significant difference from control analyzed by one-way ANOVA followed by Newman- Keuls post-test.

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Journal of Biomedical Science

ISSN: 1423-0127