Performances in behavioral assays. Behavioral tests including forced swim test (FST), tail suspension test (TST) and open field test (OFT). Time of immobility was evaluated in the FST and TST as showed in A and B separately. Numbers of crossings and rearings were counted in the OFT as showed in C and D. Each data represents mean ± SEM. *P < 0.05, ** P < 0.01, ***P < 0.001.