Figure 3From: Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell lineDown-regulation of p65 reduced expression of the anti-apoptotic genes. Cells were transiently transfected with or without over-expression of p65 and p65-targeted shRNA. Real-time PCR was performed to assess c-IAP1 (above) and BCL-2 (bottom) mRNA in the cells with GAPDH as control. Error bar indicates the standard error of the mean of three independent experiments.Back to article page