Figure 3

Depressed brain stem cardiovascular regulation in rats that survived METH intoxication. Temporal changes in averaged values of mean arterial pressure (MAP), heart rate (HR), baroreflex effectiveness index (BEI) or power density of the low-frequency (LF) component of systolic blood pressure at 20 min intervals in rats that survived intravenous administration of METH (12 or 24 mg/kg; at arrow) or their saline (Sal) controls. Values are mean ± SEM, n = 4-12 animals per experimental group. Note that whereas statistical difference (P < 0.05) versus saline group exists in the post hoc Scheffé multiple-range test at corresponding time-points, a single notation (*) is provided for clarity.