Figure 1From: Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cellsEffect of CD44 membrane distribution on the Cav1 knockdown HBMEC. DAPI was used to stain nuclear DNA (blue) and CD44 was stained with the anti-CD44 monoclonal antibody and rhodamine conjugated secondary antibody (red). Top panel: membrane distributions of CD44 without (left panel) or with (right panel) the incubation of green C. neoformans strain C1186. Lower panel: HBMEC were treated with Cav1 siRNA in the presence (right column) or absence (left column) of C. neoformans cells (strain C1186). Magnified images were boxed and shown in the bottom panel. Bar: 20 μm.Back to article page