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Figure 3 | Journal of Biomedical Science

Figure 3

From: siRNA against presenilin 1 (PS1) down regulates amyloid β42 production in IMR-32 cells

Figure 3

Effect of PS1 siRNA on the protein levels Aβ42 (a) Immunoblot analysis of Aβ42 (b) densitometric analysis. 60 μg proteins of IMR 32 cells after PS1 transfection at different concentrations were subjected to western blot analysis using anti Aβ42 antibody (1:250 dilutions). Lane 1: Non siRNA Transfected IMR-32 Cells; Lane 2: Control siRNA; Lane 3: 50 pmoles PS1siRNA; Lane 4: 75 pmoles PS1 siRNA; Lane 5:100 pmoles PS1 siRNA. Values are mean ± SD (N = 5). *** p < 0.001 significantly different from csiRNA.

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