Skip to main content

Table 3 Scatchard analysis of [3H]baclofen binding against Baclofen in the cerebral cortex of control and experimental rats

From: Decreased GABA receptor in the cerebral cortex of epileptic rats: effect of Bacopa monnieri and Bacoside-A

Group

Bmax (fmoles/mg ptn)

Kd (nM)

C

124.3 ± 8.5

1.8 ± 0.2

E

91.9 ± 6.9***

1.2 ± 0.1**

E+B

115.2 ± 7.3@@@

1.6 ± 0.3

E+D

111.7 ± 5.1@@@

1.3 ± 0.1

E+C

107.1 ± 7.7@@@

1.4 ± 0.2

  1. Values are mean ± SEM of 4-6 separate experiments. Each group consist of 6-8 rats ** p < 0.01, *** p < 0.001 when compared to control, @@ < 0.01, @@@ < 0.001 when compared to epileptic group. C- Control, E- Epileptic, E+B- Epileptic rats treated with Bacopa monnieri, E+D- Epileptic rats treated with Bacoside A and E+C- Epileptic rats treated with Carbamazepine.