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Figure 2 | Journal of Biomedical Science

Figure 2

From: Amelioration of diet-induced nonalcoholic steatohepatitis in rats by Mn-salen complexes via reduction of oxidative stress

Figure 2

Histological evaluation of rats' livers. Photographs of tissues after Hematoxylin-eosin (A-E) or Masson trichrome staining (F). Original magnifications ×100. (A) Normal liver histology of a rat fed the standard diet. (B) MCD-fed diet (NASH group) showing ballooning degeneration, pericentral macrovesicular steatosis and lobular inflammation. (C) group MCD-fed diet + EUK-8 showing normal architecture with neither steatosis nor inflammation. (D) group MCD-fed diet + EUK-134 showing normal architecture with neither steatosis nor inflammation. (E) group MCD-fed diet + Vitamin C showing normal architecture, focal macrovesicular steatosis and no inflammation. No evidences of drug toxicity have been seen in all drug treated MCD-fed group. (F) No significant fibrosis is detected in MCD-fed group. MCD: methionine and choline deficient diet.

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Journal of Biomedical Science

ISSN: 1423-0127