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Table 1 The expression of inducible and endothelial nitric oxide synthase (iNOS and eNOS) in lung tissue

From: Niacinamide mitigated the acute lung injury induced by phorbol myristate acetate in isolated rat's lungs

  

iNOS/GAPDH

eNOS/GAPDH

PMA

0

0.23 ± 0.02

0.44 ± 0.04

PMA

4

3.42 ± 0.12*

2.84 ± 0.14*

NAC

0

3.51 ± 0.14

3.02 ± 0.11

NAC

100

0.34 ± 0.04§+

2.01 ± 0.09§+

NAC

200

0.19 ± 0.06§+

1.46 ± 0.07§+

NAC

400

0.21 ± 0.04§+

0.62 ± 0.08§+

  1. Values are means ± SEM (n = 10). The data include 10 isolated lung preparations. *p < 0.05 PMA 4 vs. PMA 0. §p < 0.05 vs. NAC 0 (dose effects of NAC). +p < 0.05 vs. the values of PMA 4. PMA, phorbol myristate acetate; and NAC, niacinamide. The symbols 0 and 4 denote the dose of PMA at μg/g (lung weight), and 0, 100, 200 and 400 of NAC at mg/g (lung weight). The expression of glyceraldehyde phosphate dehydrogenase (GAPDH) was used as an internal standard.
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Journal of Biomedical Science

ISSN: 1423-0127