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Table 1 Anthropometric characteristics and serum levels of bone turnover markers

From: The relationship between osteoclastogenic and anti-osteoclastogenic pro-inflammatory cytokines differs in human osteoporotic and osteoarthritic bone tissues

 

Osteoporosis

Osteoarthritis

Age (years)

74.1 ± 7.7

71.8 ± 4.2

Sex (women/men)

17/6

23/8

Body mass index (kg/m 2 )

24.5 ± 2.3

28.3 ± 4.4**

Hip bone mineral density (g/cm 2 )

0.726 ± 0.135

0.880 ± 0.140**

Femoral neck BMD (g/cm 2 )

0.615 ± 0.098

0.757 ± 0.131**

Lumbar spine L2-L4 BMD (g/cm 2 )

0.861 ± 0.184

0.994 ± 0.193*

CTX (pmol/l)

3078(1285;5391)

3547(2183;4967)

Osteocalcin (μg/l)

6.80(0.30;11.98)

7.90(1.03;17.03)

Cathepsin K (pmol/l)

12.0(10.0;22.1)

9.4(6.7;11.3)*

RANKL (pmol/l)

0.01(0.01;0.02)

0.01(0.01;0.06)

OPG (pmol/l)

5.86(4.52;7.47)

4.42(4.09;5.01)*

  1. BMD bone mineral density. CTX C-terminal crosslinking telopeptides of type I collagen. RANKL receptor activator of nuclear factor κB ligand.
  2. OPG osteoprotegerin.
  3. Values are means ± standard deviation (with the exception of sex) and medians(25th;75th quartile) for bone turnover markers.
  4. Comparisons were assessed with Student's t-test or Mann-Whitney U test, *p < 0.05, **p < 0.001.