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Figure 1 | Journal of Biomedical Science

Figure 1

From: Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells

Figure 1

Effects of spermidine on LPS-induced NO and PGE 2 production in BV2 microglia. (A) Cells were treated with the indicated concentrations of spermidine 1 h before a 24 h LPS treatment. Amounts of NO were determined using Griess reagent and a standard curve was created using NaNO2 in culture medium. Control values were obtained in the absence of LPS or spermidine. (B) Following the manufacturer's instructions, levels of PGE2 in the media were detected using a specific enzyme immunoassay. Each value indicates the mean ± S.D. of three independent experiments. *P < 0.05 indicates a significant difference from cells treated with LPS in the absence of spermidine.

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