Figure 7
Influence of MK886 on SOD and CAT protein expression enhanced by L-carnitine in H 2 O 2 -treated HL7702 cells. HL7702 cells were pretreated with L-carnitine (1 mM) for 12 h prior to H2O2 challenge (300 μM, 12 h). MK886 (5 μM) was added to cells 2 h prior to H2O2 insult. Cu,Zn-SOD and CAT expressions were determined by western blot analysis. #P < 0.01 vs. control; **P < 0.01 vs. H2O2 alone; ΔP < 0.05 vs. L-carnitine group. The presented results are representative of three independent experiments.