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Figure 1 | Journal of Biomedical Science

Figure 1

From: Role of carotenoid β-cryptoxanthin in bone homeostasis

Figure 1

The cellular and molecular mechanism by which β-cryptoxanthin (BCX) stimulates bone formation and mineralization in osteoblastic cells. BCX may bind to orphan receptors in the nucleus of osteoblastic cells, and it stimulates gene expression of bone formation-related proteins. BCX also stimulates nuclear transcriptional activity mediated through activation of protein kinase C (PKC) or mitogen-activated protein kinase (MAPK) in osteoblastic cells.

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