Figure 1
From: Down-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications
Down-regulation of PKCζ in RCC tissues. (A) Expression of PKCζ mRNA in 3 pairs of RCC and adjacent normal kidney tissues from 3 patients by cDNA microarray analysis. Fold change compared with normal kidney tissues. Paired sample t test was used to compare PKCζ expression in the normal and RCC tissues (*P < 0.001). (B) Real-time PCR analysis of PKCζ in 5 pairs of RCC (T) and adjacent normal kidney tissues (N) from 5 patients. (C) Expression of PKCζ protein in 8 pairs of normal and RCC tissues by Western blotting analysis. β-actin was used as an internal control (D) The ration of protein intensity of PKC ζ/β-actin from Figure 1(C) was examined by densitometer analysis. Paired sample t test was used to compare PKCζ expression in the normal and RCC tissues (*P < 0.05).