Figure 3
From: Down-regulation of PKCζ in renal cell carcinoma and its clinicopathological implications
The prognostic survival of PKCζ in RCC. (A) High tumor grade was associated with short survival time in RCC patients. Tumor grade III was significantly associated with poorer outcome than grade I (P = 0.032) and II (P = 0.016) on 5-year survival, respectively. (B) High expression of PKCζ was associated with poorer clinical prognosis. The ratio of PKCζ expression (cancer/normal ratio) was PKCζ score of cancer compared with normal tissue from the same patient. The median value of all RCC patients was 0.54. PKCζ ratio > 0.54 had significantly poor survival than ratio ≤ 0.54 on 5-year survival in RCC (P = 0.042).