MDA, GSH-px and LDH assay. Production of MDA in serum and the testis was augmented and activities of GSH-px and testicular LDH were reduced by hypoxia exposure for 4 weeks in rats. These changes were attenuated by medicated (mg/kg, po) with CPU86017-RS (20, 40 and 80) and nif (10) in the last two weeks; A, Serum MDA; B. Testicular MDA; C, Serum GSH-px; D, Testicular LDH. Mean ± SD, n = 10. *P < 0.05, **P < 0.01, vs. Normal; #P < 0.05, # #P < 0.01, vs. Hypoxia, $P < 0.05, vs. H+RSL (hypoxia + RS low dose).