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Table 2 EGFR immunoexpression in relation to pathohistologic features of CCRCC (N = 94)

From: EGFR protein overexpression correlates with chromosome 7 polysomy and poor prognostic parameters in clear cell renal cell carcinoma

    Nuclear grade,
N (%)
p value Tumor size,
median (range)
p value Pathological T stage,
N (%)
p value
   1, 2 3, 4     1, 2 3, 4  
EGFR immunoexpression a,N (%) % low 33 (36.7) 12 (13.3) < 0.001b 5 (1.8-17.5) 0.011c 32 (35.6) 13 (14.4) 0.213b
   high 16 (17.8) 29 (32.2)   7 (3-16)   37 (41.1) 8 (8.9)  
  tH-score low 32 (35.9) 11 (12.4) < 0.001b 5 (1.8-17.5) 0.002c 31 (34.8) 12 (13.5) 0.354b
   high 17 (19.1) 29 (32.6)   7 (3-16)   37 (41.6) 9 (10.1)  
  cH-score low 31 (34.4) 14 (15.6) 0.006b 5 (1.8-17.5) 0.01c 33 (36.7) 12 (13.3) 0.454b
   high 18 (20) 27 (30)   7 (2.5-16)   36 (40) 9 (10)  
  1. CCRCC, clear cell renal cell carcinoma
  2. tH-score, total H-score
  3. cH-score, continuous H-score
  4. a low and high categories according to median cut off value
  5. b chi square test
  6. c Mann-Whitney U-test