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Table 3 Altered mineral content in cancerous tissues (DMBA+) vs mineral content in normal tissues (DMBA-) (μg/g wet weight)

From: The effect of dietary zinc - and polyphenols intake on DMBA-induced mammary tumorigenesis in rats

    

diets

    

elements

DMBA

Standard

Zn

Zn + resveratrol

Zn + genistein

  

Mean ± SD (n)

RSD%

Mean ± SD (n)

RSD%

Mean ± SD (n)

RSD%

Mean ± SD (n)

RSD%

Zn (μg/g)

-

17.6 ± 1.7 (5)

9.6

18.2 ± 1,3 (6)

7.1

18.5 ± 1.3 (6)

7.3

17.2 ± 2.3 (6)

13

 

+

17.6 ± 0.9 (7)

5.1

17.3 ± 1.3 (8)

7.5

19.2 ± 1.2 (8)

6.1

17.0 ± 1.1 (10)

6.6

Cu (μg/g)

-

2.57 ± 0,79 (5)

30

1.36 ± 0.22 (6)**

15

1.47 ± 0.19 (6)**

12

1.74 ± 0.45 (6)

26

 

+

2.92 ± 0.85 (7)

29

2.63 ± 0.52 (8) *

19

3.45 ± 0.82 (8) *

23

2.87 ± 0.79 (8) *

27

Fe (μg/g)

-

17.7 ± 3.1 (5)

17

18.6 ± 2.2 (6)

12

17.1 ± 2.4 (6)

13

16.3 ± 2.1 (5)

12

 

+

50.7 ± 22.6 (7) *

44

28.9 ± 6.3 (8) *

21

51.4 ± 19 (8) *

36

33.4 ± 9.6 (10) *

28

Mg (μg/g)

-

224.4 ± 33.8 (5)

15

263.5 ± 7.66 (6)

2.9

228 ± 14.7 (6)

6.4

236.8 ± 18.7 (6)

7.8

 

+

153.6 ± 10,5 (7) *

6.8

166.5 ± 11.3 (8) *

6.7

146.4 ± 12.1 (8) *

8

160.8 ± 9.3 (10) *

5.8

  1. *differences (p ≤ 0.05) between concentrations of metals in DMBA (+) and DMBA (-) groups of each type of diet
  2. **differences (p ≤ 0.05) between concentrations of metals in each type of diet (DMBA-) relative to standard diet (DMBA-)
  3. SD - standard deviation; RSD - relative standard deviation (%); n- number of samples