Figure 1

Members of the UPS are present in the proteomes of RVLM. Representative silver-stained 2-D electrophoresis gel of the rostral ventrolateral medulla (RVLM) showing the location of the protein spots studied. Results are representative of 22 individual samples from 22 animals. 1, proteasome subunit alpha type-1; 2, ubiquitin; 3, ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1). Shown also is the identification of those proteins by MALDI-TOF analysis in association with the MASCOT search program.