Figure 2From: Identification and characterization of a novel gene, c1orf109, encoding a CK2 substrate that is involved in cancer cell proliferationEffects of site-directed mutations on the c1orf109 promoter activity. HEK293 cells were transiently transfected with the −428 bp region of c1orf109 promoter constructs with different mutations of CAAT or TATA box sites. The firefly luciferase activity was assayed 24 hr after transfection and normalized to Renilla luciferase activity. Values represent the means ± S.D. of three independent experiments. * P < 0.05 versus the wild type control.Back to article page