Figure 1
Inhibition of cell viability by DATS treatment in human leukemia cells. Cells (U937, THP-1, HL60 and K562) were plated at a concentration of 2.5 x 105 cells per 60-mm plate. Following 24 h of stabilization, cells were treated with various concentrations of DATS for 48 h (A) or incubated with 20 μM of DATS for the indicated times (B). Cell viability was determined by MTT assay. Results are expressed as percentage of the vehicle treated control ± SD of three separate experiments. A Student’s t-test (*, p < 0.05 vs. untreated control) was used for determination of significance.