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Table 1 Immunostainings of Fos, CGRP, and microglia in the central nervous system of affected and unaffected mice

From: Spontaneous inflammatory pain model from a mouse line with N-ethyl-N-nitrosourea mutagenesis

  Fos CGRP Microglia
Cerebral cortex Hippocampus Spinal cord
Unaffected 71.65 ± 13.84 (n = 5) 792.33 ± 60.20 (n = 5) 146.10 ± 8.42 (n = 6) 242.83 ± 17.75 (n = 6) 213.15 ± 13.13 (n = 6)
Affected (5 weeks) 102.19 ± 13.53 (n = 8) 1512.23 ± 231.54* (n = 6) 413.85 ± 5.61* (n = 3) 593.12 ± 18.92* (n = 3) 1023.89 ± 15.04 ** (n = 3)
Affected (20 weeks)    500.79 ± 244.11 (n = 5) 361.14 ± 57.71# (n = 5) 247.78 ± 24.71# (n = 5)
  1. Values are expressed as the density of immunostaining in a standard unit area of 200 μm × 200 μm (mean ± SEM). *p < 0.05, **p < 0.01, significant difference between the unaffected and affected (5 weeks) groups. #p < 0.05, significant difference between the affected (5 weeks) and affected (20 weeks) groups.