Figure 4

Alteration of BBB permeability was compared in three methods. BBB permeability was assessed by measuring the albumin (A, C, E) and total IgG (B, D, F) contents from the CSF after hypertonic arabinose (n = 8), rTNF-α (n = 5) and FUS (n = 5) treatment. The data were expressed as the concentration (μg/ml). Statistical significance of differences in BBB permeability was calculated using Student’s t-test and are denoted by the symbol *p < 0.05.