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Table 1 1.5× down regulated growth -related genes in tbx5 knockdown embryos in different embryonic developmental stages

From: The paracrine effect of exogenous growth hormone alleviates dysmorphogenesis caused by tbx5 deficiency in zebrafish (Danio rerio) embryos

Gene Symbol

Gene Name

Genbank #

Function

Stage (hpf)

Reference

igfbp2b

insulin-like growth factor protein 2b

NM_131458

general embryonic development and growth, regulating vascular development

24

Zhou, 2008

ghra

growth hormone receptor a

NM_001083578

cytokine receptor activity

24

Di Prinzio, 2010

ing4

inhibitor of growth family, member 4

NM_001020468

regulating brain tumour growth and angiogenesis

24

Susan Nozell, 2008

mdkb

midkine-related growth factor b

NM_131716

brain development, neural crest formation

24

Liedtke, 2008

grb2

growth factor receptor-bound protein 2

NM_213035

distinct effects on neural crest and floorplate development

24

Ryan P Million, 2004

vegfaa

vascular endothelial growth factor Aa

AF016244

blood vessel endothelial cell proliferation

24

Bahary, 2007

fibpl

fibroblast growth factor (acidic) intracellular binding protein, like

NM_212861

Kupffer's vesicle development

24

Hong, 2009

pdgfab

platelet derived growth factor alpha b

NM_001076757

positive regulation of cell division

30

Eberhart, 2008

gh1

growth hormone 1

NM_001020492

growth control

30

Toro, 2009

fgf1

fibroblast growth factor 1

NM_200760

hemopoiesis

30

Songhet, 2007

vegfab

vascular endothelial growth factor Ab

NM_001044855

angiogenesis

30

Bahary, 2007

gata5

GATA-binding protein 5

NM_131235

specification of cardiomyocytes

48

Holtzinger, 2007

ghrl

ghrelin/obestatin preprohormone

NM_001083872.1

encodes ghrelin-obestatin preproprotein

48

Li, 2009