Figure 3

CLSM images of normal human epidermal melanocytes (HEM) and normal human dermal fibroblast (HDF) cell lines following incubation with RRM-MV or RRM-C. HEM cells in (A) and HDF cells in (B) were treated with 200 ng/mL or 400 ng/mL of either RRM-MV or RRM-C for 3 h, then double stained with AF488 and PI. No cytotoxic changes were detected in either cell line treated with RRM-MV.